The purpose of this research is to investigate the effectiveness of Digital Content Marketing on a Mixed Reality training platform environment with the consideration of online purchase intention through social media. E-commerce today encounters several common issues that cause customers to have reservations to purchase online. With the absence of physical contact points, customers often perceive more risks when making purchase decisions. Furthermore, online retailers often find it hard to engage customers and develop long-term relationships. In this research, a Structural (...) Equation Model is proposed to examine the efficacy of DCM from both immediate and long-term OPI. The results examine whether adopting DCM on an MR training platform environment through social media brings positive results in OPI. Empirical research was carried out through online questionnaires collected in 2021 and 2022. A total of 374 questionnaires were qualified for data analysis in this study, conducted with IBM SPSS and AMOS. The results imply that DCM is critical to stimulating both immediate and long-term OPI. The immediate OPI is positively affected by increasing perceived value through MR in DCM. Regarding the long-term OPI, increased customer engagement with DCM under MR environment can cultivate brand trust and significantly affect the long-term OPI. (shrink)

1. Ikkŭnŭn mal -- 2. Han nara ŭi yet kŭlssi ro tora kaja : K'ang Yuwei, sŏye wa mihakchŏk chŏnhwan -- 3. Chosŏn ŭi yesul ŭn illyu ŭi pigŭk ŭl tamnŭnda : Yanagi Muneyosi, minye uĭ palgyŏn -- 4. Nŏhŭi nŭn T'ap ŭi himch'am ŭl poannŭn'ga : Ko Yu-sŏp, Han'guk hyŏndae mihak ŭi t'ansaeng -- 5. Naganŭn mal.

Using covariant derivatives and the operator definitions of quantum mechanics, gauge invariant Proca and Lehnert equations are derived and the Lorenz condition is eliminated in U(1) invariant electrodynamics. It is shown that the structure of the gauge invariant Lehnert equation is the same in an O(3) invariant theory of electrodynamics.

1. 21-segi wa t'ongsŏphyŏng injae ŭi p'iryosŏng -- 2. Ch'oe Han-gi, t'ongsŏphyŏng ŭl mal hada -- 3. T'ongsŏphyŏng injae ŭi chagyŏk chokŏn -- 4. T'ongsŏphyŏng injae ŭi lidŏsip -- 5. Naganŭn mal.

This book is an anthology of various approaches to the dream and its significance, from neurophysiological, anthropological, religious, sociological, and psychological points of view. Articles in it range from extremely technical and sophisticated to rather nebulous and rambling. The phenomenon of dreaming has long perplexed man. Various approaches to it have been attempted, from the occult interpretation of dreams as signifying and portending future events, to the psychoanalytical interpretation as representing, in part, past occurrences in the life history of the (...) dreamer, to the neurophysiological investigations which correlate the electrical events of the present dream-state with other physiological and neural changes. All of the above approaches are represented in this volume. In addition, this book covers a wide spectrum of contemporary research into this problem. While not sufficiently comprehensive coverage is given to any particular aspect of dream research, it serves as a general guide to present avenues of dream investigations. Most of the essays contained therein are not too technical for the interested lay reader to comprehend.—L. P. K. (shrink)

BACKGROUND: Serotonin transporter promoter genotype appears to increase risk for depression in the context of stressful life events. However, the effects of this genotype on measures of stress sensitivity are poorly understood. Therefore, this study examined whether 5-HTTLPR genotype was associated with negative information processing biases in early childhood. METHOD: Thirty-nine unselected seven-year-old children completed a negative mood induction procedure and a Self-Referent Encoding Task designed to measure positive and negative schematic processing. Children were also genotyped for the 5-HTTLPR gene. (...) RESULTS: Children who were homozygous for the short allele of the 5-HTTLPR gene showed greater negative schematic processing following a negative mood prime than those with other genotypes. 5-HTTLPR genotype was not significantly associated with positive schematic processing. LIMITATIONS: The sample size for this study was small. We did not analyze more recently reported variants of the 5-HTTLPR long alleles. CONCLUSIONS: 5-HTTLPR genotype is associated with negative information processing styles following a negative mood prime in a non-clinical sample of young children. Such cognitive styles are thought to be activated in response to stressful life events, leading to depressive symptoms; thus, cognitive styles may index the "stress-sensitivity" conferred by this genotype. (shrink)

Purpose: A study was made of attitudes of clinical geneticists regarding the age at which minors should be allowed to undergo a carrier test and the reasons they provide to explain their answer. Methods: European clinical institutions where genetic counselling is offered to patients were contacted. 177 (63%) of the 287 eligible respondents answered a questionnaire. Results: Clinical geneticists were significantly more in favour of providing a carrier test to a younger person if the request was made together with the (...) parents than if the adolescent requested the test personally. Although a large fraction of respondents (16%–30%) were “neither unwilling nor willing” to provide a carrier test to a 16-year-old adolescent who requested the test personally, for most disorders slightly more clinical geneticists were “very willing” or “willing”. Conclusion: Age is not the only decisive element when considering the participation of adolescents in decisions affecting their health. The clinical geneticists referred to cognitive, emotional and sexual maturity and the support of parents as crucial elements in their comments regarding when to tell children about their genetic risk or to allow adolescents to request a carrier test. (shrink)

P'ŭrollogŭ : t'ongil ŭi sahoe iron ŭrosŏ hana nolli -- 1. Huch'ŏn chŏngsin kaebyŏk kwa ch'ŏnjiin habil : hana nolli ŭi ironjŏk paegyŏng kwa chŏnmang -- 2. Hana nolli ŭi hyŏngsŏng : na ŭi ironsajŏk maengnak -- 3. Hana nolli ŭi kuch'uk : charyo, kach'i chŏnje, punsŏkt'ŭl -- 4. Hana nolli ŭi Tong Asiajŏk t'odae -- 5. Hana nolli ŭi ironjŏk t'ŭksŏng kwa chihyang -- 6. Munmyŏng chŏnhwan ŭi kil : huch'ŏn chŏngsin kaebyŏk ŭl nŭkkyŏ poja -- Ep'illogŭ : kurŭm (...) yori wa sinsŏn norŭm. (shrink)

1. Pŏmbu ŭi p'ungnyu chŏngsin ch'ŏnmyŏng kwa "Hwarang oesa" kusang : kungmin todŏk seugi wa kwallyŏn hayŏ -- 2. Nae ka ponŭn Pŏmbu wa Pak Chŏng-hŭi ŭi sasŭng kwan'gye : Pak Chŏng-hŭi chipkwŏn ch'ogi ŭi chŏngch'i kihoek kwa kwallyŏn hayŏ -- 3. Han t'ojong sasangga ŭi sam kwa saenggak : iyagi ka innŭn Pŏmbu kim chŏngsŏl yŏnbo -- 4. Samin chŏngdam : chŏngch'i, kyŏngje, munhwa e kŏlch'yŏ -- 5. Yŏhaenggi : kurŭm ttara mul ttara ch'ŏlli rŭl kada.

OBJECTIVES: Early-emerging, temperamental differences in fear-related traits may be a heritable vulnerability factor for anxiety disorders. Previous research indicates that the serotonin transporter promoter region polymorphism is a candidate gene for such traits. METHODS: Associations between 5-HTTLPR genotype and indices of fearful child temperament, derived from maternal report and standardized laboratory observations, were examined in a community sample of 95 preschool-aged children. RESULTS: Children with one or more long alleles of the 5-HTTLPR gene were rated as significantly more nervous during (...) standardized laboratory tasks than children who were homozygous for the short alleles. Children homozygous for the short alleles were also rated as significantly shyer, by maternal report, than those with at least one copy of the long allele of the 5-HTTLPR gene. CONCLUSIONS: This study extends the literature linking the short alleles of the serotonin transporter promoter region polymorphism to fear and anxiety-related traits in early childhood and adulthood, and is one of very few studies to examine the molecular genetics of preschoolers' temperament using multiple measures of traits in a normative sample. (shrink)

This book is an extremely comprehensive review of the status of contemporary psychiatry, both in its theoretical and clinical aspects. While heavily dominated by a psychoanalytic bias, it explores other theoretical and clinical approaches. Included in its contents are the historical beginnings and later development of psychiatry, psychological testing and its utility for psychiatry, nosology of psychiatric disorders, various types of therapies currently in vogue, the organic as well as the psychotic disorders, psychopathic and sociopathic behavior, drug and alcohol addiction, (...) and the general usefulness of psychiatry to medicine, law, and society. The authors generally discuss the investigations and proposals of other behavioral scientists, and then offer their own view of the topic at issue. Of interest to students of philosophy are: considerations relevant to the mind-body problem, problems of normative statements inherent in attempts to determine criteria for distinguishing normal from abnormal behavior, and general matters of methodology, confirmation, and other problems in the philosophy of science which pervade all of behavioral science as well as physical science. The authors may have their personal axe to grind, but freely admit to the tenuous theoretical status of every psychodynamic system so far advanced. Their style is tedious and sometimes cumbersome. However, the book is an extremely contemporary survey, in some depth, of the state of psychiatry, and serves as a valuable reference for both lay and professional reader.—L. P. K. (shrink)

This paper argues that professionals who make boundary-related decisions should be guided by relationship-based practice. In our roles as service users and professionals, drawing from our lived experiences of professional relationships, we argue we need to move away from distance-based practice. This includes understanding the boundary stories and narratives that exist for all of us – including the people we support, other professionals, as well as the organisations and systems within which we work. When we are dealing with professional boundary (...) issues, we should centre relationship-building skills that are central to many other aspects of our work. Skills that foster relationships at all levels – between professionals, service users, and services – need to be revalued. Our final recommendation is to create, develop, and foster safer spaces within and outside of organisations, as well as inter-professionally, for the discussion and exploration of boundary-related issues and practice. We are interested in hearing from those with experiences of being marginalised by boundaries so that they can inform a reshaping of our collective ideas around boundary related practices. To foster relationship-based practices in organisations, we have outlined several recommendations here; however, we recognize that these do not go far enough, and that collective action is needed to inform systemic change. (shrink)

1. Tan'gun sinhwa ŭi wŏnhyŏngjŏk segyegwan kwa p'ungnyu chŏngsin -- 2. Wŏnhyo ŭi hwajaeng sasang kwa muaehaeng ŭi silch'ŏn -- 3. Ŭisang ŭi 'Hwaŏm ilsŭng pŏpkyedo' e nat'anan Hwaŏm sasang -- 4. Chinul ŭi Tono chŏmsu wa Chŏnghye ssangsu sasang -- 5. Sambong Chŏng To-jŏn ŭi Pulgyo paech'ŏk ŭi naeyong kwa sŏngkyŏk -- 6. T'oegye Yi Hwang ŭi ch'ŏrhakchŏk ipchang kwa 'Kyŏng' sasang -- 7. Kobong Ki Tae-sŭng ŭi hangmun chŏngsin kwa ch'ŏrhak sasang -- 8. Ugye Sŏng Hon ŭi Tohakchŏk (...) sam kwa hangmun yŏnwŏn -- 9. Yulgok Yi I ŭi Taedong sahoeron kwa ch'ŏrhakchŏk chihyang -- 10. Sŏgye Pak Se-dang ŭi Sirhakchŏk sayu ŭi kich'o -- 11. Namdang Han Wŏn-jin ŭi yŏksa insik kwa Chosŏn chunghwajuŭi -- 12. Sŏngdam Song Hwan-gi ŭi 'T'aegŭk tosŏl' haesŏk ŭi kibon ipchang -- 13. Kanjŏng Yi Nŭng-hwa 'Chosŏn Togyosa' ŭi haksulsachŏk ŭiŭi wa han'gye -- 14. Manhae Han Yong-un i pon chuch'e ŭi munje wa minjok chagyŏl ŭi wŏnch'ik. (shrink)

Background: Ethical issues related to comparative effectiveness research, or research that compares existing standards of care, have recently received considerable attention. In this paper we focus on how Ethics Review Committees should evaluate the risks of comparative effectiveness research. Main text: We discuss what has been a prominent focus in the debate about comparative effectiveness research, namely that it is justified when “nothing is known” about the comparative effectiveness of the available alternatives. We argue that this focus may be misleading. (...) Rather, we should focus on the fact that some experts believe that the evidence points in favor of one intervention, whereas other experts believe that the evidence favors the alternative. We will then introduce a case that illustrates this point, and based on that, discuss how ERCs should deal with such cases of expert disagreement. Conclusion: We argue that ERCs have a duty to assess the range of expert opinions and based on that assessment arrive at a risk judgment about the study under consideration. We also argue that assessment of expert disagreement is important for the assignment of risk level to a clinical trial: what is the basis for expert opinions, how strong is the evidence appealed to by various experts, and how can clinical trial monitoring affect the possible increased risk of clinical trial participation. (shrink)

Ethical issues related to comparative effectiveness research, or research that compares existing standards of care, have recently received considerable attention. In this paper we focus on how Ethics Review Committees should evaluate the risks of comparative effectiveness research. We discuss what has been a prominent focus in the debate about comparative effectiveness research, namely that it is justified when “nothing is known” about the comparative effectiveness of the available alternatives. We argue that this focus may be misleading. Rather, we should (...) focus on the fact that some experts believe that the evidence points in favor of one intervention, whereas other experts believe that the evidence favors the alternative. We will then introduce a case that illustrates this point, and based on that, discuss how ERCs should deal with such cases of expert disagreement. We argue that ERCs have a duty to assess the range of expert opinions and based on that assessment arrive at a risk judgment about the study under consideration. We also argue that assessment of expert disagreement is important for the assignment of risk level to a clinical trial: what is the basis for expert opinions, how strong is the evidence appealed to by various experts, and how can clinical trial monitoring affect the possible increased risk of clinical trial participation. (shrink)

The subject matter of this book is the exciting struggle of the Immanent One, who is All That There Is, to achieve ontological actuality in a mystical absorption of the collective human psyche and thereby triumph over the Transcendental Altogether Other in "a cosmic shootout at the OK Corral." And if this is none too clear, it is at least a fair sample of the kind of philosophical yellow journalese in which Braden couches his remarkable apocalyptic seizures. Matters of style (...) aside, this is a shame. For Braden's concern is the religious significance and theological implications—if any—of the so-called "psychedelic" drugs. This problem, moreover, is an open and unfulfilled invitation to some serious philosophical exploration, especially in view of some of the value-laden and cognitive claims which have been made for these pharmacological oddities. Among the numerous errors of both logic and fact, one may discern here an argument to the effect that the way to theological enlightenment is barred by the rational scientific intellect, and that the world of ordinary perception and pragmatic morals is an illusion foisted upon us by the artificialities of "Aristotelian" logic and scientific method. Thus, true to its author's private revelation, Braden's argument is not conspicuous for its logical cogency; but the author seems blissfully unaware that, insofar as he tries to present an intelligible and logically convincing case, his book is refuted by its own thesis.—H. P. K. (shrink)

Cyclin-dependent kinase 5 has been implicated in Alzheimer's disease pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5, led to increased levels of BACE1 mRNA and protein in vitro and in vivo. A p25/cdk5 responsive region containing multiple sites for signal transducer and activator of transcription was identified in the BACE1 promoter. STAT3 interacts with the BACE1 promoter, and p25-overexpressing mice had elevated levels of pSTAT3 and BACE1, whereas cdk5-deficient mice had reduced levels. Furthermore, mice with a (...) targeted mutation in the STAT3 cdk5 responsive site had lower levels of BACE1. Increased BACE levels in p25 overexpressing mice correlated with enhanced amyloidogenic processing that could be reversed by a cdk5 inhibitor. These data demonstrate a pathway by which p25/cdk5 increases the amyloidogenic processing of APP through STAT3-mediated transcriptional control of BACE1 that could have implications for AD pathogenesis. (shrink)